BDBM50001797 1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL423024

SMILES Cc1c(C2CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1

InChI Key InChIKey=OOHASZCAJGUYFP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001797   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001797(1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...)
Affinity DataIC50:  380nMAssay Description:Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001797(1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...)
Affinity DataIC50:  76nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001797(1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...)
Affinity DataIC50:  0.590nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001797(1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...)
Affinity DataIC50:  380nMAssay Description:Binding affinity at dopamine D2 receptor by [3H]-Spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed