BDBM50002324 5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperazin-1-yl}-pyrimidin-4-ol::CHEMBL140833

SMILES O=c1[nH]c(N2CCN(CCCC(O)c3ccc(F)cc3)CC2)ncc1F

InChI Key InChIKey=PEPKQWOGJXYSSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002324   

TargetSigma non-opioid intracellular receptor 1(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002324BDBM50002324(CHEMBL140833 | 5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of (+)-[3H]-3-PPP from rat cortical sigma siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002324BDBM50002324(CHEMBL140833 | 5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against radioligand [3H]spiperone binding to rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002324BDBM50002324(CHEMBL140833 | 5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]WB-4101 binding to rat cortical Alpha-1 adrenergic receptor in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed