BDBM50004536 1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione::1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione(TASO-m3T)::CHEMBL55745

SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O

InChI Key InChIKey=KZKYYGSZDVZKNJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004536   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50004536(CHEMBL55745 | 1-[4-Amino-9-(tert-butyl-dimethyl-si...)
Affinity DataEC50:  40nMAssay Description:Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50004536(CHEMBL55745 | 1-[4-Amino-9-(tert-butyl-dimethyl-si...)
Affinity DataEC50:  60nMAssay Description:Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed