BDBM50005685 2,2-Diphenyl-propionic acid 2-diethylamino-ethyl ester::2,2-Diphenyl-propionic acid 2-diethylamino-ethyl ester(Aprophen)::2-(diethylamino)ethyl 2,2-diphenylpropanoate::Aprofene::Aprophen::CHEMBL26505
SMILES CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccccc1
InChI Key InChIKey=DIDYGLSKVUKRRP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50005685
Affinity DataKi: 1.70nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 15.1nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 26.5nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 628nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M4 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 7.76E+3nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:50 percent inhibitory concentration of Butyrylcholinesterase (BChE)More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair