BDBM50006502 (+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)-acetic acid::(-)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)-acetic acid::(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)-acetic acid::CHEMBL70014

SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(Cl)cc2O1

InChI Key InChIKey=RRJBMYLAXVCLQD-SREIQFSDSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50006502   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  180nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  140nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  156nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  5.62E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed