BDBM50007289 CHEMBL100721::Sodium; 6-{2-[bis-(4-fluoro-phenyl)-methyl]-4,6-dichloro-phenoxy}-3,5-dihydroxy-hexanoate

SMILES OC(COc1c(Cl)cc(Cl)cc1C(c1ccc(F)cc1)c1ccc(F)cc1)C[C@@H](O)CC([O-])=O

InChI Key InChIKey=VQWSITRBHPOQTC-FIWHBWSRSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007289   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007289(CHEMBL100721 | Sodium; 6-{2-[bis-(4-fluoro-phenyl)...)
Affinity DataIC50:  950nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007289(CHEMBL100721 | Sodium; 6-{2-[bis-(4-fluoro-phenyl)...)
Affinity DataIC50:  950nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed