BDBM50007400 4-Phenyl-1-(4-phenyl-butyl)-piperidine::4-Phenyl-1-(4-phenyl-butyl)-piperidine: maleate::CHEMBL1788131::CHEMBL325238

SMILES C(CCc1ccccc1)CN1CCC(CC1)c1ccccc1

InChI Key InChIKey=HQGDPZPNAXRCSA-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50007400   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataKi:  0.800nMAssay Description:The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataKi:  1nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]-haloperidol in the presence of 25 nM unlabeled spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataIC50:  165nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 by using [3H]-domperidone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
New York University

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataIC50:  335nMAssay Description:Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity of the compound towards Dopamine receptor D1 in rat membranes using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed