BDBM50009421 2,2-Dimethyl-butyric acid 1-(2-{2-[4-(tert-butyl-dimethyl-silanyloxy)-6-oxo-tetrahydro-pyran-2-yl]-ethyl}-6-hydroxy-3-methyl-cyclohexyl)-3-methyl-but-3-enyl ester::CHEMBL3349540

SMILES [H][C@@]1(O)CC[C@H](C)[C@H](CC[C@@H]2C[C@H](CC(=O)O2)O[Si](C)(C)C(C)(C)C)C1[C@H](CC(C)=C)OC(=O)C(C)(C)CC

InChI Key InChIKey=AMEKTZOFUFOJDQ-POFCPJKDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009421   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009421(2,2-Dimethyl-butyric acid 1-(2-{2-[4-(tert-butyl-d...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed