BDBM50009882 CHEMBL22888::[5-{1-[1-Hydroxy-2-(2-methyl-butylcarbamoyl)-ethyl]-3-methyl-butylcarbamoyl}-5-(3-naphthalen-1-yl-2-naphthalen-1-ylmethyl-propionylamino)-pent-2-ynyl]-carbamic acid benzyl ester

SMILES CCC(C)CNC(=O)C[C@H](O)C(CC(C)C)NC(=O)C(CC#CCNC(=O)OCc1ccccc1)NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12

InChI Key InChIKey=DEKASTZDMCFHIL-NDTXXLJKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009882   

TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50009882(CHEMBL22888 | [5-{1-[1-Hydroxy-2-(2-methyl-butylca...)
Affinity DataIC50:  248nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50009882(CHEMBL22888 | [5-{1-[1-Hydroxy-2-(2-methyl-butylca...)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibitory activity against bovine cathepsin D was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50009882(CHEMBL22888 | [5-{1-[1-Hydroxy-2-(2-methyl-butylca...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed