BDBM94630 4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-morpholin-2-ylmethyl]-benzamide; citrate(AS-4370)::4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)morpholin-2-yl]methyl]benzamide;citric acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-azanyl-5-chloranyl-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-oxidanylpropane-1,2,3-tricarboxylic acid::CHEMBL60889::MLS001401439::MOSAPRIDE CITRATE::Mosapride::SMR000469200::cid_119583

SMILES CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1

InChI Key InChIKey=YPELFRMCRYSPKZ-UHFFFAOYSA-N

Data  7 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 94630   

Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi:  69.9nMAssay Description:Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi:  84nMAssay Description:Tested for affinity against 5-hydroxytryptamine 4 receptor in the myenteric plexus of the guinea pigileum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi:  200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi:  631nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi:  1.19E+3nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Alpha-1 adrenergic receptor by 3H ligand binding experiments.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1 receptor by 3H ligand binding experiments.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50:  113nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thymidylate synthase (TS) in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against dopamine receptor D2 by 3H ligand binding experiments.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50:  4.79E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPerilipin-5(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50:  2.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50:  1.97E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50:  1.27E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerotonin 2 (5-HT2) receptor(RAT)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 5-aminoimidazole-4-carboxamide AICAR formyltransferase in MOLT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed