BDBM94630 4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-morpholin-2-ylmethyl]-benzamide; citrate(AS-4370)::4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)morpholin-2-yl]methyl]benzamide;citric acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-azanyl-5-chloranyl-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-oxidanylpropane-1,2,3-tricarboxylic acid::CHEMBL60889::MLS001401439::MOSAPRIDE CITRATE::Mosapride::SMR000469200::cid_119583

SMILES CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1

InChI Key InChIKey=YPELFRMCRYSPKZ-UHFFFAOYSA-N

Data  7 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 94630   

Target5-hydroxytryptamine receptor 4(Guinea pig)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataKi:  69.9nMAssay Description:Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataKi:  84nMAssay Description:Tested for affinity against 5-hydroxytryptamine 4 receptor in the myenteric plexus of the guinea pig ileum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 113nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataKi:  200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataKi:  631nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataKi:  1.19E+3nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPerilipin-1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 1.97E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetPerilipin-5(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against alpha-2 adrenergic receptor by 3H ligand binding experiments.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 1.27E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetSerotonin 2 (5-HT2) receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2 receptor by 3H ligand binding experiments.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1 receptor by 3H ligand binding experiments.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against dopamine receptor D2 by 3H ligand binding experiments.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM94630(SMR000469200 | 4-Amino-5-chloro-2-ethoxy-N-[4-(4-f...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Alpha-1 adrenergic receptor by 3H ligand binding experiments.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed