BDBM50012392 2-(4-Methoxy-phenyl)-5-phenyl-thiazol-4-ol::CHEMBL65940

SMILES COc1ccc(cc1)-c1nc(O)c(s1)-c1ccccc1

InChI Key InChIKey=YQAKORGQQCUKEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012392   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012392(2-(4-Methoxy-phenyl)-5-phenyl-thiazol-4-ol | CHEMB...)
Affinity DataIC50:  2.40E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in human whole blood (HWBL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012392(2-(4-Methoxy-phenyl)-5-phenyl-thiazol-4-ol | CHEMB...)
Affinity DataIC50:  450nMAssay Description:Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012392(2-(4-Methoxy-phenyl)-5-phenyl-thiazol-4-ol | CHEMB...)
Affinity DataIC50:  370nMAssay Description:In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed