BDBM50012396 CHEMBL302069::Carbonic acid 2-phenyl-5-propyl-thiazol-4-yl ester propyl ester

SMILES CCCOC(=O)Oc1nc(sc1CCC)-c1ccccc1

InChI Key InChIKey=HLDFRGGMHXZOIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012396   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012396(CHEMBL302069 | Carbonic acid 2-phenyl-5-propyl-thi...)
Affinity DataIC50: 1.40E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in homogenized rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012396(CHEMBL302069 | Carbonic acid 2-phenyl-5-propyl-thi...)
Affinity DataIC50: 2.20E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in human whole blood (HWBL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012396(CHEMBL302069 | Carbonic acid 2-phenyl-5-propyl-thi...)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed