BDBM50012435 2-(4-Fluoro-phenyl)-5-phenyl-thiazol-4-ol::CHEMBL68429

SMILES Oc1nc(sc1-c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=KUOOEYKNEXFFMB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012435   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012435(2-(4-Fluoro-phenyl)-5-phenyl-thiazol-4-ol | CHEMBL...)
Affinity DataIC50:  470nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in human whole blood (HWBL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50012435(2-(4-Fluoro-phenyl)-5-phenyl-thiazol-4-ol | CHEMBL...)
Affinity DataIC50:  500nMAssay Description:Inhibition of 5-LO in rat RBL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50012435(2-(4-Fluoro-phenyl)-5-phenyl-thiazol-4-ol | CHEMBL...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed