BDBM50012834 2-Oxo-1,2,3,4-tetrahydro-5-thia-2a-aza-acenaphthylene-1-carboxylic acid (5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-amide::CHEMBL62817

SMILES FC(F)(F)c1nnc(NC(=O)C2C(=O)N3CCSc4cccc2c34)s1

InChI Key InChIKey=YRMMLXIVGRMBPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012834   

TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012834(CHEMBL62817 | 2-Oxo-1,2,3,4-tetrahydro-5-thia-2a-a...)
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012834(CHEMBL62817 | 2-Oxo-1,2,3,4-tetrahydro-5-thia-2a-a...)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed