BDBM50014094 CHEMBL3260849

SMILES CC(C)(C)NC(=O)C(N(Cc1ccc(OCc2ccc(Cl)cc2)cc1)C=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O

InChI Key InChIKey=PESUUIPTWNTJKA-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014094   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50014094(CHEMBL3260849)
Affinity DataKi:  600nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50014094(CHEMBL3260849)
Affinity DataKi:  600nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50014094(CHEMBL3260849)
Affinity DataKi:  600nMAssay Description:Inhibition of fluorescent P4 peptide binding to human MDM2 (18 to 111 or 1 to 125 residues) expressed in Escherichia coli BL21(DE3) Rosetta measured ...More data for this Ligand-Target Pair