BDBM50017811 CHEMBL467::HU::US10155732, Compound HU::hydroxyurea
SMILES NC(=O)NO
InChI Key InChIKey=VSNHCAURESNICA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50017811
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition of human CA9More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:Inhibition of human CA5aMore data for this Ligand-Target Pair
Affinity DataKi: 1.13E+5nMAssay Description:Inhibition of human CA4More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University
Curated by ChEMBL
Case Western Reserve University
Curated by ChEMBL
Affinity DataIC50: 9.97E+5nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+7nMAssay Description:Binding to stromelysin (MMP-3) in place of acetohydroxamic acid.More data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
City Of Hope
US Patent
City Of Hope
US Patent
Affinity DataIC50: 1.48E+5nMAssay Description:A diverse compound library from NCI Developmental Therapeutics Program (DTP) was subjected to a virtual screening process to identify potential RR in...More data for this Ligand-Target Pair