BDBM50021616 CHEMBL3297832

SMILES COc1c(O)ccc2c1[nH]c1c3C=CC(C)(C)Oc3cc(O)c1c2=O

InChI Key InChIKey=COUZVMMRGYONAQ-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50021616   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of CDK1 (unknown origin) assessed as inhibition of phosphate incorporation into substrate in presence of radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  220nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  210nMAssay Description:Inhibition of mouse recombinant GST-fused CLK1 expressed in Escherichia coli cells assessed as inhibition of phosphate incorporation using GRSRSRSRSR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  90nMAssay Description:Inhibition of rat DYRK1A assessed as inhibition of phosphate incorporation using GRSRSRSRSRSR and [gamma-33P]ATP as substrate after 30 mins by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK5/p25 (unknown origin) assessed as inhibition of phosphate incorporation using histone 1 and [gamma-33P]ATP as substrate after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  820nMAssay Description:Inhibition of CDK9/cyclin T (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  680nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CLK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  220nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  350nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of DYRK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  170nMAssay Description:Inhibition of CLK1 (unknown origin) assessed as inhibition of phosphate incorporation into substrate in presence of radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  75nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as inhibition of phosphate incorporation into substrate in presence of radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  210nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  680nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50021616(CHEMBL3297832)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CDK5 (unknown origin) assessed as inhibition of phosphate incorporation into substrate in presence of radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed