BDBM50026868 2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::US20240317683, Compound DMT::US20250034106, Compound DMT::WO2023019367, Compound DMT
SMILES CN(C)CCc1c[nH]c2c1cccc2
InChI Key InChIKey=DMULVCHRPCFFGV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 132 hits for monomerid = 50026868
Affinity DataEC50: 22nMAssay Description:Agonist activity at 5-HT2A receptor (unknown origin) by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
Affinity DataEC50: 28.9nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Compound was tested for the displacement of [125I]DOI from cloned human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 120 mins by sp...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Compound was tested for the displacement of [125I]DOI from clone human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 120 mins by sp...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
Affinity DataKi: 87.5nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cells incubated for 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H] 8-OH-DPAT from human recombinant 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Affinity DataKi: 101nMAssay Description:Compound was tested for the displacement of [3H]5-HT from clone human 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H] 8-OH-DPAT from human recombinant 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cells incubated for 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H] pyrilamine from human recombinant histamine H1 receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H] 8-OH-DPAT from human recombinant 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 181nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Displacement of [3H] 8-OH-DPAT from human recombinant 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H] mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Displacement of [3H] pyrilamine from human recombinant histamine H1 receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 258nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataKi: 259nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataKi: 259nMAssay Description:Compound was tested for the displacement of [3H]-8-OH- DPAT from rat brain 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H] prazosin from human recombinant adrenergic alpha-1b receptor expressed in human Chem-1 cells assessed as inhibition constant inc...More data for this Ligand-Target Pair
Affinity DataKi: 271nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [3H] prazosin from human recombinant adrenergic alpha-1a receptor expressed in human Chem-1 cells assessed as inhibition constant inc...More data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [3H] mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT2B receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 mins by sp...More data for this Ligand-Target Pair
Affinity DataKi: 335nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Displacement of [3H] pyrilamine from human recombinant histamine H1 receptor expressed in CHO-K1 cells incubated for 180 mins by spectrophotometric a...More data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT2B receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 60 mins by sp...More data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Displacement of [3H] prazosin from human recombinant adrenergic alpha-1b receptor expressed in human Chem-1 cells assessed as inhibition constant inc...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Displacement of [3H] mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT2B receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor by vacuum filtrationMore data for this Ligand-Target Pair
Affinity DataKi: 416nMAssay Description:5-HT2A Receptor Radioligand Binding. Affinity of the test compounds for the 5-HT2A receptor was determined in radioligand binding experiments with [3...More data for this Ligand-Target Pair
Affinity DataKi: 416nMAssay Description:Affinity of Compound 1 and the reference compounds DMT and 5-MeO-DMT for the 5-HT2A receptor was determined in radioligand binding experiments with [...More data for this Ligand-Target Pair
Affinity DataEC50: 440nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
Affinity DataKi: 456nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Displacement of [3H] prazosin from human recombinant adrenergic alpha-1a receptor expressed in human Chem-1 cells assessed as inhibition constant inc...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT2B receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 487nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
