BDBM50027536 (phosphonoformate)Trisodium phosphonoformate::Antiviral agent : Inhibitor of reverse transcriptase of Human T-cell lymphotropic, virus type III, useful in the treatment of HSV-1 infections::CHEMBL754::EHB-776::FOSCARNET SODIUM::Foscarnet::Foscavir::phosphonoformate trisodium salt::trisodium dioxidophosphinecarboxylate oxide::trisodium dioxidophosphinecarboxylate oxide with 6 molecules of water(foscarnet)::trisodium phosphonoformate
SMILES [O-]C(=O)P([O-])([O-])=O
InChI Key InChIKey=ZJAOAACCNHFJAH-UHFFFAOYSA-K
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50027536
Affinity DataKi: 5.60E+5nMAssay Description:Inhibition of human recombinant CA7 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.20E+5nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
Affinity DataKi: 8.20E+5nMAssay Description:Inhibition of human recombinant CA4 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.70E+5nMAssay Description:Inhibition of mouse recombinant CA13 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.29E+6nMAssay Description:Inhibition of human recombinant CA12 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.81E+6nMAssay Description:Inhibition of human recombinant CA6 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.21E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IXMore data for this Ligand-Target Pair
Affinity DataKi: 2.21E+6nMAssay Description:Inhibition of human recombinant CA9 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+6nMAssay Description:Inhibition of human recombinant CA14 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+7nMAssay Description:Inhibition of human recombinant CA5B by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.42E+7nMAssay Description:Inhibition of human recombinant CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.42E+7nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IIMore data for this Ligand-Target Pair
Affinity DataKi: 2.41E+7nMAssay Description:Inhibition of cloned human CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.17E+7nMAssay Description:Inhibition of human recombinant CA5A by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Life Science Research Center
Curated by ChEMBL
Life Science Research Center
Curated by ChEMBL
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
TargetDNA polymerase catalytic subunit(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of HSV-1 DNA polymerase in HSV-1 C42 plaque reduction assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Life Science Research Center
Curated by ChEMBL
Life Science Research Center
Curated by ChEMBL
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibitory effect of the compound on Molony Murine Leukemia virus (mo-MuLv) Recombiannt Reverse transcriptaseMore data for this Ligand-Target Pair