BDBM50030245 CHEMBL3354073
SMILES OCCCCCC1CCN(CCCN2C(=O)CCc3ccccc23)CC1
InChI Key InChIKey=QKTOQRPNKITPLN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50030245
Affinity DataKi: 4.40nMAssay Description:Antagonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as inhibition of dopamine-induced RLuc8-f...More data for this Ligand-Target Pair
Affinity DataKi: 447nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 468nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 603nMAssay Description:Displacement of [3H]NMS from human M2 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 676nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.91E+3nMAssay Description:Displacement of [3H]NMS from human M3 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.57E+3nMAssay Description:Displacement of [3H]NMS from human M5 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.62E+3nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by beta-arrestin engagement ...More data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+4nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein eng...More data for this Ligand-Target Pair
Affinity DataEC50: 204nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Antagonist activity at human SP/Myc epitope-tagged muscarinic M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced mVen...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as inhibition of dopamine-induced mVenus-...More data for this Ligand-Target Pair
Affinity DataIC50: 3.31E+3nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein act...More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human M4 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein act...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based beta-arrestin ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+4nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein eng...More data for this Ligand-Target Pair