BDBM69864 (3-methoxyphenyl)-(2-phenylquinazolin-4-yl)amine::CHEMBL541845::MLS001174264::N-(3-methoxyphenyl)-2-phenyl-4-quinazolinamine::N-(3-methoxyphenyl)-2-phenyl-quinazolin-4-amine::N-(3-methoxyphenyl)-2-phenylquinazolin-4-amine::SMR000589153::cid_4841865

SMILES COc1cccc(Nc2nc(nc3ccccc23)-c2ccccc2)c1

InChI Key InChIKey=GSIQYCKOUGIZQC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 69864   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69864((3-methoxyphenyl)-(2-phenylquinazolin-4-yl)amine |...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM69864((3-methoxyphenyl)-(2-phenylquinazolin-4-yl)amine |...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells preincubated for 30 mins prior to Hoechst 33342 addition measured every 60 secs up to 120 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Biofor

Curated by ChEMBL
LigandPNGBDBM69864((3-methoxyphenyl)-(2-phenylquinazolin-4-yl)amine |...)
Affinity DataIC50:  760nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed