BDBM50033307 (4-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine::CHEMBL118538

SMILES Clc1ccc(Nc2nc(nc3ccccc23)-c2ccccc2)cc1

InChI Key InChIKey=MIMFNRPHMYSQMK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033307   

LigandPNGBDBM50033307((4-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine...)
Affinity DataIC50: 830nMAssay Description:Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50033307((4-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine...)
Affinity DataIC50: 830nMAssay Description:Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50033307((4-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine...)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed