BDBM50033991 3-(2,4-Difluoro-phenyl)-1-(2-{[2-(4,5-diphenyl-1H-imidazol-2-ylsulfanyl)-ethyl]-methyl-amino}-ethyl)-1-(2-morpholin-4-yl-ethyl)-urea::CHEMBL11400

SMILES CN(CCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)CCN(CCN1CCOCC1)C(=O)Nc1ccc(F)cc1F

InChI Key InChIKey=JDCWWINOFGMBJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033991   

TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033991(3-(2,4-Difluoro-phenyl)-1-(2-{[2-(4,5-diphenyl-1H-...)
Affinity DataIC50: 240nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed