BDBM50034510 CHEMBL3359272

SMILES CC(C)N1CCC[C@H]1CNC(=O)c1cn(C2CCCC2)c(=O)c2n(C)c3ccccc3c12

InChI Key InChIKey=OEYYOVRNPJSWTO-UHFFFAOYSA-N

Data  4 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50034510   

TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  1.32E+3nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assay in presence of EC20 of GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  1.82E+3nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assay in presence of EC20 of GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  8.40E+3nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assay in presence of EC20 of exena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  8.51E+3nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assay in presence of EC20 of exena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  3.00E+4nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assay in presence of EC20 of lirag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034510(CHEMBL3359272)
Affinity DataEC50:  3.16E+4nMAssay Description:Positive allosteric modulation of human recombinant GLP1 receptor expressed in 9-3-H cells by calcium mobilization assay in presence of EC20 of lirag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed