BDBM50035139 1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-4-trifluoromethylspiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]::CHEMBL60608

SMILES Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)OCc2c3cccc2C(F)(F)F)c2ccccc12

InChI Key InChIKey=SZKLZVMYXKMBTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035139   

TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035139(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-4-tr...)
Affinity DataIC50: 2.60nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035139(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-4-tr...)
Affinity DataIC50: 180nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed