BDBM50036288 4-Dimethylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL332471

SMILES CN(C)c1ccc(cc1)S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=WCXNJFBONDLQBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036288   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50036288(4-Dimethylamino-N-(3,4-dimethyl-isoxazol-5-yl)-ben...)
Affinity DataIC50:  8.40E+4nMAssay Description:Ability to inhibit [125I]-ET1 binding to vascular smooth muscle (vsm)- A10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50036288(4-Dimethylamino-N-(3,4-dimethyl-isoxazol-5-yl)-ben...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed