BDBM50039241 1-{2-[(4-Methoxy-3-trifluoromethyl-phenyl)-phenyl-(3-trifluoromethyl-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid::CHEMBL77166

SMILES COc1ccc(cc1C(F)(F)F)C(OCCN1CCCC(C1)C(O)=O)(c1ccccc1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=JLPFRSGXRAQFON-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039241   

TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039241(1-{2-[(4-Methoxy-3-trifluoromethyl-phenyl)-phenyl-...)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039241(1-{2-[(4-Methoxy-3-trifluoromethyl-phenyl)-phenyl-...)
Affinity DataIC50:  2.01E+5nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039241(1-{2-[(4-Methoxy-3-trifluoromethyl-phenyl)-phenyl-...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039241(1-{2-[(4-Methoxy-3-trifluoromethyl-phenyl)-phenyl-...)
Affinity DataIC50:  2.12E+5nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed