BDBM50039247 1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid::CHEMBL405620

SMILES COc1ccc(cc1)C(OCCN1CCC=C(C1)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1

InChI Key InChIKey=YTEOXXBKHDDXII-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039247   

TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039247(1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-1,2,...)
Affinity DataIC50:  2.80E+6nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039247(1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-1,2,...)
Affinity DataIC50:  2.68E+5nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039247(1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-1,2,...)
Affinity DataIC50:  1.08E+6nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039247(1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-1,2,...)
Affinity DataIC50:  2.66E+6nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed