BDBM50039818 1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-butyl)-piperazine; hydrochloride::CHEMBL311275::CHEMBL543139
SMILES C(CCc1ccccc1)CN1CCN(CC1)c1cccc2OCCOc12
InChI Key InChIKey=ZKRPGPXPNMTYOU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50039818
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories
Curated by ChEMBL
Solvay Duphar Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories
Curated by ChEMBL
Solvay Duphar Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.324nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 6.80nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 2)More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 1)More data for this Ligand-Target Pair