BDBM50040282 CHEMBL317029::CHEMBL545249::cis-3-Chloro-6-dimethylamino-8-phenyl-5,6,7,8-tetrahydro-naphthalen-2-ol; hydrochloride

SMILES CN(C)C1CC(c2ccccc2)c2cc(O)c(Cl)cc2C1

InChI Key InChIKey=XZCKHECUBFUSAR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040282   

TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040282(CHEMBL317029 | CHEMBL545249 | cis-3-Chloro-6-dimet...)
Affinity DataIC50:  0.708nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040282(CHEMBL317029 | CHEMBL545249 | cis-3-Chloro-6-dimet...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040282(CHEMBL317029 | CHEMBL545249 | cis-3-Chloro-6-dimet...)
Affinity DataIC50:  0.710nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040282(CHEMBL317029 | CHEMBL545249 | cis-3-Chloro-6-dimet...)
Affinity DataIC50:  1.48E+3nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using [3H]ditolylguanidine (DTG) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed