BDBM50041735 1-(2,6-Diisopropyl-phenyl)-3-[1-(4-dimethylamino-phenyl)-cyclopentylmethyl]-urea; hydrochloride::CHEMBL46423::CHEMBL542103
SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(CCCC1)c1ccc(cc1)N(C)C
InChI Key InChIKey=PKKNCEXEVUFFFI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50041735
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory activity against ACAT was determined in rabbit intestinal microsome from cholesterol-fed animalsMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Tested for in vitro inhibition against Acyl coenzyme A:cholesterol acyltransferase of intestinal microsomes in cholesterol-fed rabbitsMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 2(Human)
National Institute On Alcohol Abuse and Alcoholism
Curated by ChEMBL
National Institute On Alcohol Abuse and Alcoholism
Curated by ChEMBL
Affinity DataIC50: 368nMAssay Description:Inhibition of human SOAT2 expressed in mouse AC29 cellsMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Human)
National Institute On Alcohol Abuse and Alcoholism
Curated by ChEMBL
National Institute On Alcohol Abuse and Alcoholism
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human SOAT1 expressed in mouse AC29 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Tested for in vitro inhibition against Acyl coenzyme A:cholesterol acyltransferase of intestinal microsomes in cholesterol-fed rabbitsMore data for this Ligand-Target Pair