BDBM50042495 CHEMBL120362::N-[(2,6-diphenyl-2H-chromen-3-yl)methyl]-N-hydroxyurea

SMILES NC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1c1ccccc1

InChI Key InChIKey=AGWZVHUGWRALAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042495   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042495(CHEMBL120362 | N-[(2,6-diphenyl-2H-chromen-3-yl)me...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042495(CHEMBL120362 | N-[(2,6-diphenyl-2H-chromen-3-yl)me...)
Affinity DataIC50:  320nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed