BDBM50044283 CHEMBL3356893

SMILES CCNC(=O)Nc1nc2ccc(cc2s1)-c1cncc(OC)c1

InChI Key InChIKey=NRQJNWMHLPKGKI-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044283   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Vertex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50044283(CHEMBL3356893)Copy SMILESCopy InChI

Affinity DataKi:  7nMAssay Description:Inhibition of PI3K-gamma (unknown origin) using [33P]ATP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Vertex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50044283(CHEMBL3356893)Copy SMILESCopy InChI

Affinity DataKi:  52nMAssay Description:Inhibition of PI3K-alpha (unknown origin) using [33P]ATP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI