BDBM50045361 (20RS)-6-Ethyl-6-hydroxy-9,11-dihydro-6H-8-oxa-4,10a-diaza-benzo[b]fluorene-7,10-dione::CHEMBL90136

SMILES CCC1(O)C(=O)OCc2c1cc1-c3ncccc3Cn1c2=O

InChI Key InChIKey=SWPAFTNGLCVMGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045361   

TargetDNA topoisomerase 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045361((20RS)-6-Ethyl-6-hydroxy-9,11-dihydro-6H-8-oxa-4,1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed