BDBM50045366 (20RS)-Sodium; 2-(1-amino-8-hydroxymethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-7-yl)-2-hydroxy-butyrate::CHEMBL314025

SMILES CCC(O)(C([O-])=O)c1cc2-c3nc4cccc(N)c4cc3Cn2c(=O)c1CO

InChI Key InChIKey=MHKQCKWRWFVLGF-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045366   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045366((20RS)-Sodium; 2-(1-amino-8-hydroxymethyl-9-oxo-9,...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed