BDBM50045741 3-[4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-1-phenyl-propan-1-one::3-[4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-1-phenyl-propan-1-one (+)-(3R), (4R)-6::3-[4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-1-phenyl-propan-1-one (-)-(3S), (4S)-6::CHEMBL94345

SMILES C[C@H]1CN(CCC(=O)c2ccccc2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=IQGJBVSSFDCTAJ-HTAPYJJXSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045741   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045741(3-[4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-y...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards mu opioid receptor by displacement of [3H]-NAL from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045741(3-[4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-y...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards mu opioid receptor by displacement of [3H]-NAL from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045741(3-[4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-y...)
Affinity DataKi:  163nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at 10 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045741(3-[4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-y...)
Affinity DataKi:  163nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed