BDBM50045762 3-[3,4-Dimethyl-1-(2-thiophen-2-yl-ethyl)-piperidin-4-yl]-phenol::CHEMBL330138

SMILES C[C@H]1CN(CCc2cccs2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=DGEXSDIRTDWGOA-HNAYVOBHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50045762   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045762(3-[3,4-Dimethyl-1-(2-thiophen-2-yl-ethyl)-piperidi...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity towards mu opioid receptor by displacement of [3H]-NAL from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045762(3-[3,4-Dimethyl-1-(2-thiophen-2-yl-ethyl)-piperidi...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at 10 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045762(3-[3,4-Dimethyl-1-(2-thiophen-2-yl-ethyl)-piperidi...)
Affinity DataKi:  72nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]-NAL at 10 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed