BDBM50045855 2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13-yl)-N,N-dipropyl-acetamide::CHEMBL327952

SMILES CCCN(CCC)C(=O)Cc1c2-c3ccccc3CCCn2c2ccccc12

InChI Key InChIKey=HXVSILAMVOCHRQ-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50045855   

TargetTranslocator protein(Rattus norvegicus (rat))
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataKi:  328nMAssay Description:Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]naxolone binding to opiate receptors in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed