BDBM500473 7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino]-4-[6- (trifluorometh- yl)imidazo[1,2- a]pyridin-3- yl[isoindolin-1-one::US11021481, Compound I-132::US11078201, Compound I-132::US11548890, Compound I-132

SMILES OC1CCN(CC1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnc3ccc(cn23)C(F)(F)F)nc1

InChI Key InChIKey=ZKTVSRCOYNHNSO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500473   

LigandPNGBDBM500473(US11021481, Compound I-132 | 7-[[5-(4- hydroxy-1- ...)
Affinity DataIC50: 750nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500473(US11021481, Compound I-132 | 7-[[5-(4- hydroxy-1- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500473(US11021481, Compound I-132 | 7-[[5-(4- hydroxy-1- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500473(US11021481, Compound I-132 | 7-[[5-(4- hydroxy-1- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500473(US11021481, Compound I-132 | 7-[[5-(4- hydroxy-1- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent