BDBM50048755 4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-benzoylamino)-5-oxo-pentanoylamino]-benzoic acid::CHEMBL280832

SMILES OC(=O)c1ccc(NC(=O)CCC(NC(=O)c2cc(Cl)cc(Cl)c2)C(=O)N2CCC3(CCCC3)CC2)cc1

InChI Key InChIKey=DZZCNFRSQJZKRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048755   

TargetGastrin/cholecystokinin type B receptor(Human)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048755(4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50: 568nMAssay Description:In vitro inhibition of gastrin-induced [Ca2+] cytosolic elevation in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50048755(4-[5-(8-Aza-spiro[4.5]dec-8-yl)-4-(3,5-dichloro-be...)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of binding of [3H]N-Me-N-Leu-CCK-8 to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed