BDBM50049596 6-(4-Methoxy-phenylsulfanylmethyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL23911
SMILES COc1ccc(SCc2cnc3nc(N)nc(N)c3c2C)cc1
InChI Key InChIKey=YYBYCBOPPNOBID-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50049596
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair