BDBM50050395 6-[(2,5-Dimethoxy-phenylamino)-methyl]-pteridine-2,4-diamine::CHEMBL23402

SMILES COc1ccc(OC)c(NCc2cnc3nc(N)nc(N)c3n2)c1

InChI Key InChIKey=KWOLNABVXFXBBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050395   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050395(6-[(2,5-Dimethoxy-phenylamino)-methyl]-pteridine-2...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050395(6-[(2,5-Dimethoxy-phenylamino)-methyl]-pteridine-2...)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050395(6-[(2,5-Dimethoxy-phenylamino)-methyl]-pteridine-2...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed