BDBM50050399 6-[(2-Methoxy-6-methyl-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL281131

SMILES COc1cccc(C)c1NCc1cnc2nc(N)nc(N)c2c1C

InChI Key InChIKey=LPYIJIDVSVXJAA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050399   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050399(6-[(2-Methoxy-6-methyl-phenylamino)-methyl]-5-meth...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050399(6-[(2-Methoxy-6-methyl-phenylamino)-methyl]-5-meth...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050399(6-[(2-Methoxy-6-methyl-phenylamino)-methyl]-5-meth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed