BDBM50050418 6-(2-Naphthalen-1-yl-ethyl)-pteridine-2,4-diamine::CHEMBL276954

SMILES Nc1nc(N)c2nc(CCc3cccc4ccccc34)cnc2n1

InChI Key InChIKey=ASMUCKGLVFZVRS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050418   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050418(6-(2-Naphthalen-1-yl-ethyl)-pteridine-2,4-diamine ...)
Affinity DataIC50:  820nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050418(6-(2-Naphthalen-1-yl-ethyl)-pteridine-2,4-diamine ...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050418(6-(2-Naphthalen-1-yl-ethyl)-pteridine-2,4-diamine ...)
Affinity DataIC50:  9.70E+4nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed