BDBM50050470 1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazol-3-yl]-piperidine::CHEMBL58296

SMILES Clc1ccc(CN2CCC(CC2)c2cc(on2)-c2ccc(Cl)cc2)cc1

InChI Key InChIKey=IGAYGUGEWYBNRY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50050470   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050470(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazo...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D4 expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050470(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazo...)
Affinity DataKi:  44nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK-293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050470(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazo...)
Affinity DataKi:  160nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050470(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazo...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050470(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazo...)
Affinity DataKi:  430nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050470(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazo...)
Affinity DataKi:  430nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK-293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed