BDBM50051592 CHEMBL2369902::[(2S,3R)-beta-MePhe3] Dynorphin A analogues::[(2S,3S)-beta-MePhe3] Dynorphin A analogues

SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6@@H](-[#6])-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#7])=O

InChI Key InChIKey=LLLZIUPVYZVZTF-PUEAZXOZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051592   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50051592(CHEMBL2369902 | [(2S,3R)-beta-MePhe3] Dynorphin A ...)
Affinity DataIC50:  6nMAssay Description:Inhibition of binding [3H]U-69,539 at Opioid receptor kappa 1 of guinea pig brain membrane (GPB) homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50051592(CHEMBL2369902 | [(2S,3R)-beta-MePhe3] Dynorphin A ...)
Affinity DataIC50:  6nMAssay Description:Agonistic activity towards Opioid receptor delta 1 was determined by evaluating the inhibitory activity towards electrically stimulated mouse vas def...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50051592(CHEMBL2369902 | [(2S,3R)-beta-MePhe3] Dynorphin A ...)
Affinity DataIC50:  112nMAssay Description:Inhibition of binding [3H]-DAMGO at Opioid receptor mu 1 of guinea pig brain membrane (GPB) homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed