BDBM50051759 1-{3-[4-(1-Ethyl-propyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl}-propan-1-one::CHEMBL314919

SMILES CCC(CC)c1ccc(cc1)C1CC2CCC(C1C(=O)CC)N2C

InChI Key InChIKey=QRTMYRXFCOZLFS-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051759   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50051759(1-{3-[4-(1-Ethyl-propyl)-phenyl]-8-methyl-8-aza-bi...)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50051759(1-{3-[4-(1-Ethyl-propyl)-phenyl]-8-methyl-8-aza-bi...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-nisoxatine from Norepinephrine transporter of rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50051759(1-{3-[4-(1-Ethyl-propyl)-phenyl]-8-methyl-8-aza-bi...)
Affinity DataIC50:  270nMAssay Description:Displacement of [125I]-RTI-55 from dopamine transporter of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed