BDBM50051881 1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[1,3]dioxan-5-yl]-butyl}-3,5-dimethyl-1H-pyrazole::CHEMBL30860
SMILES Cc1cc(C)n(CCCCC2(C)COC(OC2)c2nc(c([nH]2)-c2ccccc2)-c2ccccc2)n1
InChI Key InChIKey=MTDRWJLSTNOLOR-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50051881
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
Affinity DataIC50: >500nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% of the Acyl coenzyme A:cholesterol acyltransferase 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% of the Acyl coenzyme A:cholesterol acyltransferase 1 ...More data for this Ligand-Target Pair
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:choleste...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholest...More data for this Ligand-Target Pair