BDBM50052019 CHEMBL89768::L-660771::MK-571::Sodium; 3-[{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionate::Sodium;3-[{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionate::sodium (E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(3-(dimethylamino)-3-oxopropylthio)methylthio)propanoate

SMILES CN(C)C(=O)CCSC(SCCC([O-])=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1

InChI Key InChIKey=AXUZQJFHDNNPFG-UHFFFAOYSA-M

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50052019   

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50052019(L-660771 | MK-571 | Sodium; 3-[{3-[(E)-2-(7-chloro...)
Affinity DataIC50: 1.5nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In DepthDetails Article

TargetMultidrug resistance-associated protein 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50052019(L-660771 | MK-571 | Sodium; 3-[{3-[(E)-2-(7-chloro...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50052019(L-660771 | MK-571 | Sodium; 3-[{3-[(E)-2-(7-chloro...)
Affinity DataIC50: 7.57E+3nMAssay Description:Inhibition of human MRP1 in human 2008 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50052019(L-660771 | MK-571 | Sodium; 3-[{3-[(E)-2-(7-chloro...)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of human MRP2 expressed in dog MDCK2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50052019(L-660771 | MK-571 | Sodium; 3-[{3-[(E)-2-(7-chloro...)
Affinity DataIC50: 2.5nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In DepthDetails Article