BDBM50053559 4-[3-(7-Imidazol-1-ylmethyl-5-phenyl-naphthalen-2-yloxymethyl)-phenyl]-tetrahydro-pyran-4-ol::CHEMBL129566

SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(cc(Cn4ccnc4)cc3c2)-c2ccccc2)c1

InChI Key InChIKey=ZVKQRMTWYASLHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053559   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053559(4-[3-(7-Imidazol-1-ylmethyl-5-phenyl-naphthalen-2-...)
Affinity DataIC50:  640nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed